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=== Monoclonal antibody drugs {{nobold|1=(type=mab)}}{{anchor|1=Monoclonal antibody drugs}}=== {{anchor|1=Monoclonal antibody drugs}} * {{para|type|mab}} This form the box uses parameters: <syntaxhighlight lang="wikitext" style="overflow: auto"> | type = mab <!-- Monoclonal antibody data --> | mab_type = | source = | target = </syntaxhighlight> For example [[Catumaxomab]]: {{Infobox drug | drug_name = Catumaxomab | type = mab <!-- Monoclonal antibody data --> | mab_type = 3funct | source = axo | target = [[EpCAM]], [[CD3 (immunology)|CD3]] }} <syntaxhighlight lang="wikitext" style="overflow: auto"> | type = mab <!-- Monoclonal antibody data --> | mab_type = 3funct | source = axo | target = [[EpCAM]], [[CD3 (immunology)|CD3]] </syntaxhighlight> '''mab_type''' defines one of the following types of antibody or antibody fragment: {| class = "wikitable" |- ! {{para|mab_type|}} || output |- | mab || Whole antibody |- | Fab || [[Fab fragment]] |- | F(ab')2 || [[Fab fragment|F(ab')<sub>2</sub> fragment]] |- | Fab' || [[Fab' fragment]] |- | scFv || [[Single-chain variable fragment]] |- | di-scFv || Di-[[single-chain variable fragment]] |- | sdAb || [[Single domain antibody]] |- | 3funct || [[Trifunctional antibody]] |- | clFab || [[Chemically linked Fab]] |- | BiTE || [[Bi-specific T-cell engager]] |} '''source''' is the species on which the protein sequence of the antibody is based: {| class = "wikitable" |- ! {{para|source|}} || output |- | a || [[Rat]] |- | e || [[Hamster]] |- | i || [[Primate]] |- | o || [[Mouse]] |- | u || [[Human]] |- | xi/a, xi/e, ''etc.'' || [[Chimeric antibody|Chimeric]] ([[rat]]/human) ''etc.'' |- | xi || [[Chimeric antibody|Chimeric]] ''[generic, use only if values above are not applicable]'' |- | zu/a, zu/e, ''etc.'' || [[Humanized]] (from [[rat]]) ''etc.'' |- | zu || [[Humanized]] ''[generic, use only if values above are not applicable]'' |- | xizu/a, xizu/e, ''etc.'' || [[Chimeric antibody|Chimeric]]/[[humanized]] hybrid ([[rat]]/human) ''etc.'' |- | xizu || [[Chimeric antibody|Chimeric]]/[[humanized]] hybrid ''[generic, use only if values above are not applicable]'' |- | axo || [[Rat]]/[[mouse]] hybrid |} '''target''' is the antigen at which the antibody is directed. This parameter takes free text as value, preferably including a wikilink such as {{para|target|<nowiki>[[TNF-α]]</nowiki>}}. The drug name is followed by a "?" linked to [[Nomenclature of monoclonal antibodies]], saving the need to explain how each monoclonal antibody has been named. '''Shortened Monoclonal antibody form:''' <syntaxhighlight lang="wikitext" style="overflow: auto"> {{Infobox drug | type = mab | image = | alt = | caption = <!-- Monoclonal antibody data --> | mab_type = <!-- mab, Fab, F(ab')2, Fab', scFv, di-scFv, 3funct, clFab, BiTE --> | source = <!-- a, e, i, o, u, xi/a, zu/a, xizu/a, axo, ... --> | target = <!-- antigen, not the code number of the monoclonal antibody! --> <!-- Clinical data --> | pronounce = | tradename = | Drugs.com = | MedlinePlus = | pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = | ATC_prefix = <!-- 'none' when not assigned --> | ATC_suffix = <!-- Legal status --> | legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled --> | legal_AU_comment = | legal_BR = <!-- OTC, A1, A2, A3, B1, B2, C1, C2, C3, C5, D1, D2, E, F1, F2, F3, F4 --> | legal_BR_comment = | legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII --> | legal_CA_comment = | legal_DE = <!-- Anlage I, II, III or Unscheduled --> | legal_DE_comment = | legal_NZ = <!-- Class A, B, C --> | legal_NZ_comment = | legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM / Class A, B, C --> | legal_UK_comment = | legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V --> | legal_US_comment = | legal_EU = | legal_EU_comment = | legal_UN = <!-- N I, II, III, IV / P I, II, III, IV --> | legal_UN_comment = | legal_status = <!-- For countries not listed above --> <!-- Pharmacokinetic data --> | bioavailability = | protein_bound = | metabolism = | metabolites = | onset = | elimination_half-life = | duration_of_action= | excretion = <!-- Identifiers --> | CAS_number = | PubChem = | DrugBank = | KEGG = }} </syntaxhighlight>
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